Resources

In the archive you can find documentation of the PCaVision journey from the beginning– from awards and grants to journal articles and theses covering the science behind PCaVision.

2024
August 1
Clinical Trial Protocol: Clinical Validation of Multiparametric Ultrasound for Detecting Clinically Significant Prostate Cancer Using Computer-Aided Diagnosis: A Direct Comparison with the Magnetic Resonance Imaging Pathway

D.L. van den Kroonenberg, A. Jager, A. Garrido-Utrilla, J.B. Reitsma, A.W. Postema, H.P. Beerlage, J.R. Oddens, European Urology Open Science, vol. 66, pp. 60-66, 2024.

2023
March 1
Clinical Trial Protocol: Developing an Image Classification Algorithm for Prostate Cancer Diagnosis on Three-dimensional Multiparametric Transrectal Ultrasound ?

A. Jager, A.W. Postema, M. Mischi, H. Wijkstra, H.P. Beerlage, J.R. Oddens, European Urology Open Science, vol. 49, pp. 32-43, 2023.

January 26
Best Paper Award

2nd place, ex equo from the IEEE EMBS Benelux Chapter at the 9th Dutch Biomedical Engineering Conference, Jan 26-27, 2023, for the best Transactions published by IEEE EMBS in 2021-2022. Paper: C. Chen, R. Perera, M. C. Kolios, H. Wijkstra, A. A. Exner, M. Mischi, S. Turco, “Pharmacokinetic modeling of…
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2022
October 13
IEEE IUS Super-Resolution Challenge 2022

Runner up award for the in-vivo section for Tristan Stevens, Elizabeth Herbst, Ben Luijten, Boudewine Ossenkoppele, Thierry Voskuil, Shiying Wang, Jihwan Youn, Claudia Errico, Nicola Pezzotti, Massimo Mischi, Ruud van Sloun, “A Hybrid deep learning pipeline for improved ultrasound localization microscopy,” IEEE IUS, Venice (Italy), Oct. 10-13, 2022.

September 23
Radiomics in prostate cancer imaging ?

  L. Brunese, P. Martino, M. Mischi, M. Prasad, A. Santone, Editorial, Frontiers in Oncology, 12, 2022.

September 1
Pharmacokinetic modeling of PSMA targeted nanobubbles for quantification of extravasation and binding in mice models of prostate cancer ?

C. Chen, R. Perera, M.C. Kolios, H. Wijkstra, A.A. Exner, M. Mischi, S. Turco, Med Phys. 2022; 1– 13.

August 10
The unique second wave phenomenon in contrast enhanced ultrasound imaging with nanobubbles ?

C. Chen, R. Perera, M.C. Kolios, H. Wijkstra, A.A. Exner, M. Mischi, S. Turco, Scientific Reports, vol. 12, no. 1, pp. 1-12, 2022.

June 17
Pharmacokinetic modeling of the Second-wave Phenomenon in Nanobubble-based Contrast-enhanced Ultrasound ?

C. Chen, R. Perera, M. C. Kolios, H. Wijkstra, A. A. Exner, M. Mischi, S. Turco, IEEE Trans on Biomedical Engineering.

April 27
Interpretable machine learning for characterization of focal liver lesions by contrast-enhanced ultrasound ?

S. Turco, T. Tiyarattanachai, K. Ebrahimkheil, J. Eisenbrey, A. Kamaya, M. Mischi, A. Lyshchik, A. El Kaffas, IEEE T-UFFC, vol. 69, no. 5, pp. 1670-1681, 2022.

January 18
Nonlinear ultrasound for cancer diagnostics ?

Panfilova, A. (2022). Eindhoven University of Technology.

January 1
Acoustic characterization of tissue-mimicking materials for ultrasound perfusion imaging research ?

P. Chen, A. Pollet, S. Turco, J. den Toonder, H. Wijkstra, M. Mischi, Ultrasound in Medicine and Biology, vol. 48, no. 1, pp. 124-142, 2021.

2021
November 1
Experimental acoustic characterisation of an endoskeletal antibubble contrast agent: first results ?

A. Panfilova, P. Chen, R.J.G. van Sloun, H. Wijkstra, M. Postema, A.T. Poortinga, M. Mischi, Medical Physics, vol. 48, no. 11, pp. 6765-6780, 2021.

July 29
The challenge of prostate biopsy guidance in the era of mpMRI detected lesion: ultrasound-guided versus in-bore biopsy ?

A. Jager, K. Vilanova, M. Mischi, H. Wijkstra, J.R. Oddens, British Journal of Radiology, vol. 94: 20210363, 2021.

April 1
A review on B/A measurement methods with a clinical perspective ?

A. Panfilova, R.J.G. van Sloun, H. Wijkstra, O.A. Sapozhnikov, M. Mischi, Journal of the Acoustical Society of America, 149(9):2200-37, 2021.

March 1
Super-resolution Ultrasound Localization Microscopy through Deep Learning ?

R.J.G. van Sloun, O. Solomon, M. Bruce, Zin Z. Khaing, H. Wijkstra, Y.C. Eldar, M. Mischi, IEEE Trans Med Imaging, 40(3):829-39, 2021.

January 22
Novel pathways in the diagnosis of prostate cancer ?

Christophe Koenraad Mannaerts, Amsterdam UMC (Location AMC), January 21, 2021.

2020
December 1
Synthetic Elastography Using B-Mode Ultrasound Through a Deep Fully Convolutional Neural Network ?

R. R. Wildeboer J. G. van Sloun, C. K. Mannaerts, P. H. Moraes, G. Salomon, M. C. Chammas, H. Wijkstra, and M. Mischi, IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, vol. 67, no. 12, pp. 2640-2648, 2020.

December 1
National Institutes of Health Grant

Prostate Cancer Diagnosis by Multiparametric Ultrasound (€1.5M)

November 1
Contrast Enhanced Ultrasound with dispersion analysis for the localization of prostate cancer – correlation with radical prostatectomy specimens ?

M. Gayet, A. Postema, R.J.G. van Sloun, C. Mannaerts, R.R. Wildeboer, C.D. Savciheijink, S.G. Schalk, A. Kajtazovic, H. v.d. Poel, P. Mulders, H. Beerlage, M. Mischi, H. Wijkstra, W J Urol, vol. 38, no. 11, pp. 2811-2818, 2020.

October 29
Advanced Ultrasound in Prostate Cancer Care ?

Arnoud Postema, Amsterdam UMC (Location AMC), October 29, 2020.

October 1
Detection of clinically significant prostate cancer in biopsy?naïve men: direct comparison of systematic biopsy, multiparametric MRI and contrast?ultrasound?dispersion imaging?targeted biopsy ?

C.K. Mannaerts, M.R. Engelbrecht, A.W. Postema, R.A. van Kollenburg, C.M. Hoeks, C.D. Savci?Heijink, R.J.G. Van Sloun, R.R. Wildeboer, T.M. de Reijke, M. Mischi, H. Wijkstra, BJU international, vol. 126, no. 4, pp. 481-493, 2020.

October 1
NWO/TTW OTP Grant

Quantitative 4D contrast-enhanced ultrasound imaging for accurate diagnosis of benign and malignant uterine disorders (€750,000 + €200,000 industrial contribution)

September 18
Prostate cancer, clinical implications of new diagnostic means ?

Maudy Gayet, Eindhoven University of Technology, Sep. 18, 2020.

August 1
Blind Source Separation for Clutter and Noise Suppression in Ultrasound Imaging: Review for Different Applications ?

R.R. Wildeboer, F. Sammali, R.J.G. van Sloun, Y. Huang, P. Chen, M. Bruce, C. Rabotti, H. Wijkstra, M. Mischi, IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, vol. 67, no. 8, pp. 1495-1512, 2020.

June 1
Artificial intelligence in multiparametric prostate cancer imaging with focus on deep-learning methods ?

R.R. Wildeboer, R.J.G. van Sloun, H. Wijkstra, M. Mischi, Computers Methods and Programs in Biomedicine, vol. 189, 105316, 2020.

March 1
Contrast-enhanced ultrasound quantification: from kinetic modeling to machine learning ?

S. Turco, P. Frinking, R.R. Wildeboer, M. Arditi, H. Wijkstra, J.R. Lindner, M. Mischi, Ultrasound in Med & Biol, vol. 46, no. 3, pp. 518-554, 2020.

February 1
Automated multiparametric localization of prostate cancer based on B-mode, shear-wave elastography, and contrast-enhanced ultrasound radiomics ?

R.R. Wildeboer, C.K. Mannaerts, R.J. van Sloun, L. Budäus, D. Tilki, H. Wijkstra, G. Salomon, M. Mischi, European Radiology, vol. 30, no. 2, pp. 806-815, 2020.

January 17
Best Poster Award

25th European Symposium on Ultrasound Contrast Imaging, Rotterdam (NL), January 16-17, 2020. Poster: S. Turco, R. Perera, E. Peri., H. Wijkstra, A.A. Exner, M. Mischi, “Pharmacokinetic modeling of targeted ultrasound nanobubbles to quantify PSMA expression in prostate cancer”.

January 1
Contrast-Enhanced Ultrasound (CEUS) ?

C.K. Mannaerts, R.A.A. van Kollenburg, R.J.G van Sloun, R.R. Wildeboer, M. Mischi, H.P. Beerlage, H. Wijkstra, Interventional Urology, 2nd ed, Springer Nature, 2020.

2019
December 1
Multiparametric ultrasound for prostate cancer detection and localization: Correlation of B-mode, shearwave elastography and contrast-enhanced ultrasound with radical prostatectomy specimens ?

C. K. Mannaerts, R.R. Wildeboer, S. Remmers, R.A. van Kollenburg , A. Kajtazovic, J. Hagemann, A. W. Postema, R.J. van Sloun , M.J. Roobol, D. Tilki, M. Mischi, H. Wijkstra, G. Salomon, Journal of Urol, vol. 222, no. 6, pp. 1166-1173, 2019.

December 1
European Research Council Proof of Concept

M. Mischi: Implementation of contrast-ultrasound dispersion imaging for better prostate cancer care (€150,000)

December 1
Hanarth Fonds fellowship, artificial intelligence in oncology

S. Turco, Integrating genomics and imaging for improved prostate cancer care (€250,000)

August 1
Super-Resolution Contrast Enhanced Ultrasound Methodology for the Identification of in-Vivo Vascular Dynamics in 2D ?

E. Kanoulas, M. Butler, C. Rowley, V. Voulgaridou, K. Diamantis, K.A.A. Fox, W.C. Duncan, A. McNeilly, M. Averkiou, H. Wijkstra, M. Mischi, R.S. Wilson, W. Lu, V. Sboros, Invest Radiol, vol. 54, no. 8, pp. 500, 2019.

June 19
Multiparametric and Multidimensional – A Three-Dimensional and Multiparametric Approach to Ultrasound Imaging of Prostate Cancer ?

Rogier Rudolf Wildeboer, Eindhoven University of Technology, 2020.

June 1
EFSUMB Young Investigator Award

Euroson 2019, May 30-June1, 2019, Granada (Spain), by Rogier Wildeboer, R.J.G. van Sloun, H. Wijkstra, M. Mischi, “3D Multiparametric Ultrasound for Prostate Cancer Diagnosis”.

May 16
3-D multi-parametric contrast-enhanced ultrasound for the prediction of prostate cancer ?

R. Wildeboer, R.J.G van Sloun, P. Huang, H. Wijkstra, M. Mischi, Ultrasound in Medicine and Biology, vol. 45, no. 10, pp. 2713-2724, 2019.

April 16
Three-dimensional greyscale transrectal ultrasound-guidance and biopsy core preembedding for detection of prostate cancer: Dutch clinical cohort study ?

A.A.M.A. van der Aa, C.K. Mannaerts, M.C.W. Gayet, J.C. van der Linden, B.P. Schrier, J.P.M. Sedelaar, M. Mischi, H.P. Beerlage, H. Wijkstra, BMC Urology, vol. 19, no. 1, pp. 1-9, 2019.

April 10
View DocumentDeep learning for real-time, automatic and scanner-adapted prostate (zone) segmentation of TRUS for e.g. MRI-TRUS Fusion Prostate Biopsy

R. van Sloun, R.R. Wildeboer, C.K. Mannaerts, A. W. Postema, M. Gayet, H.P. Beerlage, G. Salomon, H. Wijkstra, M. Mischi, European Urology Focus, 2019.

February 1
On the relationship between dynamic contrast-enhanced ultrasound parameters and the underlying vascular architecture extracted from acoustic angiography, ?

A. Panfilova, S.E. Shelton, C. Caresio, R.J.G. van Sloun, F. Molinari, H. Wijkstra, P.A. Dayton, M. Mischi, Ultrasound in Med and Biol, vol. 45, no. 2, pp. 539-548, 2019.

January 18
Best Poster Award

24th European Symposium on Ultrasound Contrast Imaging, Rotterdam (NL), January 17-18, 2019. Poster: S. Turco, R. Perera, H. Wijkstra, A. A. Exner, M. Mischi, “Pharmacokinetic analysis of targeted nanonubbles for quantitative assessment of PSMA expression in prostate cancer”.

January 1
Contrast enhanced ultrasound in urology ?

R.R. Wildeboer, J.J.M.C.H. de la Rosette, M. Mischi, H. Wijkstra, Smith’s Textbook of Endourology – 4th Edition, Wiley, 2019.

2018
December 1
Convective-Dispersion Modeling in Three-Dimensional Contrast-Ultrasound Imaging for the Localization of Prostate Cancer ?

R. R. Wildeboer, R. J. G. van Sloun, S. G. Schalk, C. K. Mannaerts, J. C. van der Linden, P. Huang, H. Wijkstra, M. Mischi, IEEE Trans on Medical Imaging, vol. 37, no. 12, pp. 2593-2602, 2018.

December 1
4TU Grant

Precision Medicine by integrating functional imaging and advanced machine learning (€4M)

November 8
Multiparametric ultrasound: evaluation of greyscale, shear wave elastography and contrast-enhanced ultrasound for prostate cancer detection and localization in correlation to radical prostatectomy specimens ?

C.K. Mannaerts, R.R. Wildeboer, A.W. Postema, J. Hagemann, L. Budäus,  D. Tilki,  M. Mischi, H. Wijkstra,  G. Salomon, BMC Urolology, vol. 18(98), pp. 1-10 2018.

November 1
Evaluation of magnetic-resonance dispersion imaging for improved prostate cancer diagnosis through a multicenter study, ?

S. Turco, C. Lavini, S. Heijmink, J. Barentsz, H. Wijkstra, and M. Mischi, American Journal of Roentgenology, vol. 211, no. 5, pp. W242-W251, 2018.

October 2
Contrast-enhanced ultrasound tractography for 3D vascular imaging of the prostate ?

R.J.G. van Sloun, L. Demi, S. Schalk, C. Caresio, C.K. Mannaerts, H. vd Linden, P. Huang, H. Wijkstra, M. Mischi, Nature Scientific Reports, vol. 8, no. 1, pp. 14240, 2018.

October 1
Quantification of Contrast Kinetics in Clinical Imaging ?

M. Mischi, S. Turco, O. Soliman, F. ten Cate, H. Wijkstra, I. Schoots, Springer, October 2018.

September 17
Pharmacokinetic modeling of targeted ultrasound contrast agents for quantitative assessment of anti-angiogenic therapy: a longitudinal case-control study in colon cancer ?

S. Turco, A. El Kaffas, J. Zhou, A. Lutz, H. Wijkstra, J.K. Willmann, M. Mischi, Molecular Imaging and Biology, pp. 1-11, 2018.

July 20
Accurate validation of ultrasound imaging for prostate cancer: challenges in registration of imaging and histopathology ?

R.R Wildeboer, R.J.G. van Sloun, A.W. Postema, C.K. Mannaerts, M. Gayet, H. Beerlage, H. Wijkstra, M. Mischi, J of Ultrasound, vol. 21, no. 3, pp. 197-207, 2018.

February 1
Concordance of Gleason grading with three-dimensional ultrasound systematic biopsy and biopsy core pre-embedding ?

A.A.M.A. van der Aa, C.K. Mannaerts, H. van der Linden, M. Gayet, B. Ph. Schrier, M. Mischi, H.P. Beerlage H. Wijkstra, W J Urology, pp. 1-7, 2018.

January 19
Best Poster Award

23rd European Symposium on Ultrasound Contrast Imaging, Rotterdam (NL), January 18-19, 2018. Poster: R. Wildeboer, R. van Sloun, S. Schalk, C. Mannaerts, van der Linden, P. Huang, H. Wijkstra, M. Mischi, “Prostate cancer localization through convective-dispersion estimation in 3-dimensional contrast ultrasound”.

January 17
Ultrasound markers for cancer ?

Ruud Sloun, Eindhoven University of Technology, 2018.

2017
December 3
3D quantitative contrast ultrasound for prostate cancer localization ?

S.G. Schalk, J. Huang, L. Demi, H. Wijkstra, P. Huang, M. Mischi, Ultras Med Biol, vol. 44, no. 4, 807-814, 2018.

December 1
Best Poster Award

2nd Place, 16th Belgian day on Biomedical Engineering joint meeting with the Annual Meeting of the IEEE EMBS Benelux Chapter, Brussels, Belgium, Nov 30 – Dec 1, 2017. Poster: S. Turco, A. El Kaffas, P. Frinking, I. Tardy, J.K. Willmann, H. Wijkstra, M. Mischi, “Pharmacokinetic modeling of targeted microbubbles: Applications…
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December 1
NWO/TTW OTP Grant

Integrated platform to design novel cancer localization strategies by US microvasculature imaging (€744,000 + €265,000 industrial contribution)

December 1
Spatiotemporal correlation of ultrasound-contrast-agent dilution curves for angiogenesis localization by dispersion imaging ?

M. P. J. Kuenen, T. A. Saidov, H. Wijkstra, and M. Mischi, Correspondence in IEEE Trans. on Ultrasonics, Ferrorelectrics, and Frequency Control, vol. 60, no. 12, pp. 2665-2669, 2013.

November 1
Viscoelasticity mapping by identification of local shear wave dynamics ?

R.J. van Sloun, R.R. Wildeboer, H. Wijkstra, M. Mischi, IEEE T-UFFC, vol. 64, no. 11, pp. 1666-1673, 2017.

September 25
EFSUMB Young Investigator Award

Euroson 2017, Sep 22-25, Ljubljana, (Slovenia) by R.J.G. van Sloun, H. Wijkstra, M. Mischi, “Prostate cancer localization with contrast-enhanced ultrasound – from technical innovation to clinical implementation”.

August 1
Multiparametric Dynamic Contrast-Enhanced Ultrasound Imaging of Prostate Cancer ?

R. Wildeboer, A. Postema, L. Demi, M. Kuenen, H. Wijkstra, M. Mischi, Eur Radiol, vol. 27, no. 8, pp. 3226–3234, 2017.

May 18
Three-dimensional histopathological reconstruction as a reliable ground truth for prostate cancer studies ?

R. Wildeboer, S. Schalk, L. Demi, H. Wijkstra, M. Mischi, Biomedical Physics & Engineering Express, vol. 3, no. 3, pp. 1-13, 2017.

April 5
The prostate cancer detection rates of CEUS-targeted versus MRI-targeted versus systematic TRUS-guided biopsies in biopsy-naïve men: a prospective, comparative clinical trial using the same patients ?

A.W. Postema, M.J.V. Scheltema, C.K. Mannaerts, R.J.G. van Sloun, T. Idzenga, M. Mischi, M.R.E. Engelbrecht, J.J.M.C.H. De la Rosette, H. Wijkstra, BMC Urology 17(27), pp. 1-8, 2017.

April 1
Mammography: developing a smarter and safer alternative ?

R. van Sloun, L. Demi, H. Wijkstra, M. Mischi, Editorial on Future Oncology, vol. 13, no. 8, pp. 669-671, 2017.

March 1
Entropy of Ultrasound-Contrast-Agent Velocity Fields for Angiogenesis Imaging in Prostate Cancer ?

R.J. van Sloun, L. Demi, A. Postema, J.J. De La Rosette, H. Wijkstra, M. Mischi, IEEE Trans on Medical Imaging, vol. 36, no. 3, pp. 826-837, 2017.

March 1
Contrast-enhanced Ultrasound Angiogenesis Imaging by Mutual Information Analysis for Prostate Cancer Localization ?

S.G. Schalk, L. Demi, N. Bouhouch, M.P.J. Kuenen, A.W. Postema, J.J.M.C.H. de la Rosette, H. Wijkstra, T. Tjalkens, M. Mischi, IEEE Trans on Biomedical Engineering, vol. 64, no. 3, pp. 661-670, 2017.

February 27
Quantitative ultrasound molecular imaging by modeling the binding kinetics of targeted contrast agent ?

S. Turco, I. Tardy, P. Frinking, H. Wijkstra, M. Mischi, Physics in Medicine and Biology, vol. 62, pp. 2449-2464, 2017.

January 20
Best Poster Award

22nd European Symposium on Ultrasound Contrast Imaging, Rotterdam (NL), January 19-20, 2017. Poster: R.R. Wildeboer, A. Postema, L. Demi, M.P.J. Kuenen, H. Wijkstra, M. Mischi, “Multiparametric approach for dynamic contrast-enhanced ultrasound imaging of prostate cancer”.

January 18
Pharmacokinetic Modeling in cancer: from functional to molecular imaging of angiogenesis ?

Simona Turco, Eindhoven University of Technology, 2018.

January 18
Towards 3D prostate cancer localization by contrastultrasound dispersion imaging ?

Stefan Schalk, Eindhoven University of Technology, 2017.

January 17
Best Paper Award

1st place, IEEE EMBS Benelux Chapter at the 6th Dutch Biomedical Engineering Conference for the best Transactions published by IEEE EMBS in 2015-16, Egmond aan Zee (NL), Jan. 26-27, 2017. Paper: R.J. van Sloun, L. Demi, A. Postema, J.J. De La Rosette, H. Wijkstra, M. Mischi, “Entropy of Ultrasound-Contrast-Agent Velocity…
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January 17
Best Paper Award

3rd place, IEEE EMBS Benelux Chapter at the 6th Dutch Biomedical Engineering Conference for the best Transactions published by IEEE EMBS in 2015-16, Egmond aan Zee (NL), Jan. 26-27, 2017. Paper: S. Turco, H. Wijkstra, M. Mischi, “Mathematical models of contrast-agent transport kinetics for imaging of cancer angiogenesis: a review,” IEEE…
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2016
November 16
Entropy of Ultrasound-Contrast-Agent Velocity Fields for Angiogenesis Imaging in Prostate Cancer ?

IEEE T-MI, November 2016. Paper: R.J. van Sloun, L. Demi, A. Postema, J.J. De La Rosette, H. Wijkstra, M. Mischi, IEEE Trans on Medical Imaging, vol. 36, no. 3, pp. 826-837, 2017.

October 5
Towards Dynamic Contrast Specific Ultrasound Tomography ?

L. Demi, R.J.G. van Sloun, H. Wijkstra, M. Mischi, Nature: Scientific Reports, 2016; 6: 34458.

October 1
Ultrasound-Contrast-Agent Dispersion and Velocity Imaging for Prostate Cancer Localization ?

R. van Sloun, L. Demi, A. Postema, J.J. De La Rosette, H. Wijkstra, M. Mischi, Medical Image Analysis, vol. 35, pp. 610-619, 2017.

August 1
Fractal dimension of tumor microvasculature by DCE-US: preliminary study in mice ?

T. Saidov, C. Heneweer, M.P.J. Kuenen, H. Wijkstra, M. Mischi, Ultrasound in Medicine and Biology, vol. 42, no. 12, pp. 2852-2863, 2016.

July 1
Imaging modalities in focal therapy: multiparametric ultrasound ?

R. R. Wildeboer, A. P. Panfilova, M. Mischi, H. Wijkstra, Archivos Españoles de Urologica, vol. 69(6), pp. 281-290, 2016.

June 22
Mathematical models of contrast-agent transport kinetics for imaging of cancer angiogenesis: a review ?

S. Turco, H. Wijkstra, M. Mischi, IEEE Reviews in Biomedical Engineering, vol. 9, pp. 121-147, 2016.

January 25
3D Navigo™ versus TRUS guided prostate biopsy in prostate cancer detection ?

M. Gayet, A. van der Aa, P. Schmitz, H.P. Beerlage, B.Ph. Schrier, P.F.A. Mulders, M. Mischi, H. Wijkstra, World Journal of Urology, vol. 34, no. 9, pp. 1255-1260, 2016.

January 1
Contrast-Enhanced Ultrasound and Elastrography imaging ?

T. Idzenga, H. Truong, H. Wijkstra, A.W. Postema, M. Mischi, J.J.M.C.H De la Rosette, E. J. Trabulsi, Part II, Chapter 9, pp. 125-138, Interventional Urology, Springer, 2016.

January 1
3D Surface-based Registration of Ultrasound and Histology in Prostate Cancer Imaging ?

S. Schalk, A. Postema, T.A. Saidov, L. Demi, M. Smeenge, J.J.M.C.H. de la Rosette, H. Wijkstra, and M. Mischi, Computerized Medical Imaging and Graphics, vol. 47, pp. 29-39, 2016.

2015
November 17
Time-efficient Estimation of the Magnetic Resonance Dispersion Model Parameters for Quantitative Assessment of Angiogenesis ?

S. Turco, A. J. E. M. Janssen, C. Lavini, J. J. de la Rosette, H. Wijkstra, and M. Mischi, Biomedical Signal Processing & Control, vol. 26, pp. 23–33, 2016.

November 7
Cumulative phase delay imaging for contrast-enhanced ultrasound tomography ?

Physics in Medicine and Biology, 2015. Paper: L. Demi, R. van Sloun, H. Wijkstra, M. Mischi, Physics in Medicine and Biology, vol. 60, pp. L23–L33, 2015.

November 7
Cumulative phase delay imaging for contrast-enhanced ultrasound tomography ?

L. Demi, R. van Sloun, H. Wijkstra, M. Mischi, Physics in Medicine and Biology, vol. 60, no. 21, 2015, pp. L23-L33.

July 9
Ultrasound coefficient of nonlinearity imaging ?

IEEE T-UFFC, August 2015. Paper: R.J. van Sloun, L. Demi, C. Shan, M. Mischi, IEEE Trans on Ultrasonics, Ferroelectrics, and Frequency Control, vol. 62, no. 7, pp. 1331-1341, 2015.

July 1
Ultrasound coefficient of nonlinearity imaging ?

R.J. van Sloun, L. Demi, C. Shan, M. Mischi, IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, vol. 62, no. 7, pp. 1331-1341, 2015.

May 1
4D Spatiotemporal Analysis of Ultrasound-contrast-agent Dispersion for Prostate Cancer Localization: a Feasibility Study ?

S.G. Schalk, L. Demi, M. Smeenge, D.M. Mills, K.D. Wallace, J.J.M.C.H. de la Rosette, H. Wijkstra, M. Mischi, IEEE Trans on Ultrasonics, Ferroelectrics, and Frequency Control, vol. 62, no. 5, pp. 839-851, 2015.

May 1
Ultrasound modalities and quantification: developments of Multi-parametric ultrasonography, a new modality to detect, localize and target prostatic tumors ?

A. Postema, T. Idzenga, M. Mischi, P. Frinking, J. de la Rosette, H. Wijkstra, Current Opinion in Urology, vol. 25, no. 3, pp. 191-197, 2015.

February 1
Multiparametric ultrasound in the detection of prostate cancer: a systematic review ?

A. Postema, M. Mischi, J. De la Rosette, H. Wijkstra, World Journal of Urology, vol. 33, no. 11, pp 1651-1659, 2015.

January 23
Best Poster Award

20th European Symposium on Ultrasound Contrast Imaging, Rotterdam (NL), January 22-23, 2015. Poster: S. Schalk, L. Demi, S. Martijn, J. de la Rosette, H. Wijkstra, and M. Mischi, “3D Contrast-Ultrasound Dispersion Imaging by Mutual Information Analysis in Prostate Cancer”.

January 1
Contrast-Enhanced Ultrasonography ?

M. Smeenge, M. Mischi, M. P. Laguna, J. J. M. C. H. de la Rosette and H. Wijkstra, Chapter 12, Current Clinical Urology – Imaging and Focal Therapy of Early Prostate Cancer, Editor: Thomas J. Polascik, pp. 155-164, Springer Science+Business Media, ISBN 978-1-62703-181-3, 2013.

January 1
Contrast-ultrasound dispersion imaging for prostate cancer localization ?

Maarten Kuenen, Eindhoven University of Technology, 2014.

2014
October 24
Transabdominal contrast-enhanced ultrasound imaging of the prostate ?

M. Mischi, L. Demi, M. Smeenge, M.P.J. Kuenen, A.W. Postema, J.J.M.C.H. de la Rosette, H. Wijkstra, Ultrasound in Med & Biol, vol. 41, no. 5, pp. 1112-1118, 2015.

October 3
Cumulative phase delay between second harmonic and fundamental components – a marker for ultrasound contrast agents ?

L. Demi, H. Wijkstra, M. Mischi, J Acoustic Society America, vol. 136, pp. 2968-75, 2014. 

August 1
MR dispersion imaging for localization of angiogenesis and cancer growth ?

M. Mischi, S. Turco, C. Lavini, K. Kompatsiari, J.J.M.C.H. de la Rosette, M. Breeuwer, and H. Wijkstra, Investigative Radiology, vol. 49, no. 8, pp. 561-569, 2014.

April 15
Best Poster Award

29th Conference of the European Association of Urology, Stockholm (Sweden), April 11-15, 2014. Poster: M. Mischi, M.P.J. Kuenen, H.P Beerlage, J.J.M.C.H. de la Rosette, H. Wijkstra, “Prostate cancer localization by contrast-ultrasound-dispersion imaging: results from a pilot study”.

January 27
Maximum likelihood estimation for indicator dilution analysis ?

M.P.J. Kuenen, I.H.F. Herold, H.H.M. Korsten, J.J.M.C.H. de la Rosette, H. Wijkstra, and M. Mischi, IEEE Transactions on Biomedical Engineering, vol. 61, no. 3, pp. 821-831, 2014.

January 24
Best Poster Award

19th European Symposium on Ultrasound Contrast Imaging, Rotterdam (NL), January 23-24, 2014. Poster: Bouhouch, L. Demi, M. Kuenen, H. Wijkstra, T. Tjalkens, and M. Mischi, “Contrast-enhanced angiogenesis imaging by mutual information analysis”.

January 19
EFSUMB Young Investigator Award

Euroson 2014 in Tel Aviv (Israel) by M.P.J. Kuenen, H.P. Beerlage, J.J.M.C.H. de la Rosette, H. Wijkstra, and M. Mischi, “Contrast-ultrasound dispersion imaging for prostate cancer localization: comparison between imaging and histopathology”.

January 1
Contrast-ultrasound dispersion imaging for prostate cancer localization by improved spatiotemporal similarity analysis ?

M.P.J. Kuenen, H. Wijkstra, M. Mischi, Ultrasound in Med. & Biol, vol. 39, no. 9, pp. 1631-1641, 2013.

2013
December 6
Best Paper Award

IEEE EMBS Benelux Chapter at the Joint 12th Belgian Day on Biomedical Engineering and Annual Symposium of the IEEE-EMBS Benelux Chapter, Brussels (B), Dec. 5-6, 2013. Paper: M.P.J. Kuenen, I.H.F. Herold, H.H.M. Korsten, J.J.M.C.H. de la Rosette, H. Wijkstra, and M. Mischi, “Maximum likelihood estimation for indicator dilution analysis”, IEEE…
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December 1
Dutch Cancer Society (KWF) Grant

Improved prostate cancer detection and localization by contrast enhanced dispersion imaging (€560,000)

2012
December 1
European Research Council Starting Grant

M. Mischi: Prostate Cancer localization by contrast ultrasound angiogenesis imaging (€1.5M)

September 7
Angiogenesis in prostate cancer: onset, progression and imaging ?

G. Russo, M. Mischi, W. Scheepens, J. de la Rosette, H. Wijkstra, British Journal of Urology International, vol. 110, no. 11c, pp. E794–E808, December 2012.

May 1
Prostaatkankerlokalisatie met ‘dispersion’ echografie ?

M. Mischi, M. Kuenen, J. de la Rosette, W. Scheepens, H. Wijkstra, Tijdschrift voor Urologie, vol. 2, no. 3, pp. 67-68, 2012.

April 26
Angiogenesis imaging by spatiotemporal analysis of ultrasound-contrast-agent dispersion kinetics ?

M. Mischi, M.P.J. Kuenen, H. Wijkstra, IEEE Trans on UFFC, vol. 54, no. 4, pp. 621-629, April 2012.

March 30
Role of Transrectal Ultrasound in Focal Therapy of Prostate Cancer: Report from a Consensus Panel ?

M. Smeenge, J. Barentsz, D. Cosgrove, J de la Rosette, T. de Reijke, S. Eggener, F. Frauscher, G. Kovacs, S.F. Matin, M. Mischi, P. Pinto, A. Rastinehad, O. Rouviere, G. Salomon, T. Polascik, J. Walz, H. Wijkstra, M. Marberger, BJU-International, vol. 110, no. 7, pp. 942-948, 2012.

2011
December 1
Best Innovator Group (BIG) Grant

Best Innovator Group (BIG) Award of the Eindhoven University of Technology (M. Mischi, €27,000)

March 3
Novel contrast-enhanced ultrasound imaging in prostate cancer ?

M. Smeenge, M. Mischi, M.P. Laguna Pes, J.J.M.C.H. de la Rosette, H. Wijkstra, World J Urology, vol. 29, no. 5, pp. 581-587, 2011.

March 1
Contrast-Ultrasound Diffusion Imaging for Localization of Prostate Cancer ?

M.P.J. Kuenen, M. Mischi, H. Wijkstra, IEEE Trans. on Medical Imaging, vol. 30, no. 8 , pp. 1493-1502, 2011.

2009
December 1
Dutch Research Council Grant

NWO/TTW Vidi grant (M. Mischi):  Prostate cancer detection by contrast-ultrasound diffusion imaging (€800,000)

2008
February 11
Best Paper Award

IOP Select 2008 for the best journal papers by the Institute of Physics. Paper: M. Mischi, J.A. den Boer, H.H.M. Korsten, “On the physical and stochastic representation of an indicator dilution curve as a gamma variate,” Physiological Measurements, vol. 29, pp. 281-294, 2008.